In silico investigations into lysosomal arrhythmia causation
During intracellular calcium overload, ryanodine receptors (RyRs) spontaneously release calcium, which can result in delayed afterdepolarizations that are strongly linked to potentially fatal arrhythmias. The sarcoplasmic reticulum acts as the primary calcium store in cardiomyocytes. Other organelle...
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| Format: | Thesis |
| Language: | English |
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2024
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