In silico investigations into lysosomal arrhythmia causation

During intracellular calcium overload, ryanodine receptors (RyRs) spontaneously release calcium, which can result in delayed afterdepolarizations that are strongly linked to potentially fatal arrhythmias. The sarcoplasmic reticulum acts as the primary calcium store in cardiomyocytes. Other organelle...

Полное описание

Библиографические подробности
Главный автор: Meng, Z
Другие авторы: Burton, RAB
Формат: Диссертация
Язык:English
Опубликовано: 2024
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