IGF-1R expression is associated with HPV-negative status and adverse survival in head and neck squamous cell cancer

Head and neck squamous cell carcinomas (HNSCC) are treated with surgery, radiotherapy and cisplatin-based chemotherapy, but survival from locally-advanced disease remains poor, particularly in patients whose tumors are negative for Human papillomavirus (HPV). Type 1 IGF receptor (IGF-1R) is known to...

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Bibliographic Details
Main Authors: Dale, OT, Aleksic, T, Shah, KA, Han, C, Mehanna, H, Rapozo, DCM, Sheard, JDH, Goodyear, P, Upile, NS, Robinson, M, Jones, TM, Winter, S, Macaulay, VM
Format: Journal article
Language:English
Published: Oxford University Press 2015