Characterization of the interaction between tumor necrosis factor-stimulated gene-6 and heparin: implications for the inhibition of plasmin in extracellular matrix microenvironments.

TSG-6, the secreted product of tumor necrosis factor-stimulated gene-6, is not constitutively expressed but is up-regulated in various cell-types during inflammatory and inflammation-like processes. The mature protein is comprised largely of contiguous Link and CUB modules, the former binding severa...

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Bibliographic Details
Main Authors: Mahoney, D, Mulloy, B, Forster, M, Blundell, C, Fries, E, Milner, C, Day, A
Format: Journal article
Language:English
Published: 2005