Comparison of the sensitivity of in vivo and in vitro assays for detection of antiviral cytotoxic T cell activity.

Sensitivities of in vitro and in vivo assays for the detection of lymphocytic choriomeningitis virus (LCMV)-specific CTL were compared. Measurement of primary cytotoxicity was the least sensitive of all the tested assays. However, when the same 51Cr release assays were performed after in vitro resti...

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Bibliographic Details
Main Authors: Castelmur, I, DiPaolo, C, Bachmann, M, Hengartner, H, Zinkernagel, R, Kündig, T
Format: Journal article
Language:English
Published: 1993