The role of catechol-O-methyltransferase in reward processing and addiction.

Catechol-O-methyltransferase (COMT) catabolises dopamine and is important for regulating dopamine levels in the prefrontal cortex. Consistent with its regulation of prefrontal cortex dopamine, COMT modulates working memory and executive function; however, its significance for other cognitive domains...

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Bibliographic Details
Main Authors: Tunbridge, E, Huber, A, Farrell, S, Stumpenhorst, K, Harrison, P, Walton, M
Format: Journal article
Language:English
Published: 2012