Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia
Altered metabolism is a hallmark of cancer. However, the role of genomic changes in metabolic genes driving the tumour metabolic shift remains to be elucidated. Here, we have investigated the genomic and transcriptomic changes underlying this shift across ten different cancer types.A systematic pan-...
Asıl Yazarlar: | Haider, S, McIntyre, A, van Stiphout, R, Winchester, L, Wigfield, S, Harris, A, Buffa, F |
---|---|
Materyal Türü: | Journal article |
Dil: | English |
Baskı/Yayın Bilgisi: |
BioMed Central
2016
|
Benzer Materyaller
-
The tumour hypoxia induced non-coding transcriptome.
Yazar:: Choudhry, H, ve diğerleri
Baskı/Yayın Bilgisi: (2016) -
Gene expression signatures as biomarkers of tumour hypoxia
Yazar:: Harris, B, ve diğerleri
Baskı/Yayın Bilgisi: (2015) -
Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis.
Yazar:: Jubb, A, ve diğerleri
Baskı/Yayın Bilgisi: (2010) -
The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer (TNBC)
Yazar:: Harris, A, ve diğerleri
Baskı/Yayın Bilgisi: (2016) -
Metabolic Shift and Hyperosmolarity Underlie Age-Related Macular Degeneration
Yazar:: Laurent Schwartz, ve diğerleri
Baskı/Yayın Bilgisi: (2024-09-01)