Synchronised infection identifies early rate‐limiting steps in the hepatitis B virus life cycle

Hepatitis B virus (HBV) is an enveloped DNA virus that contains a partially double‐stranded relaxed circular (rc) DNA. Upon infection, rcDNA is delivered to the nucleus where it is repaired to covalently closed circular (ccc) DNA that serves as the transcription template for all viral RNAs. Our unde...

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Những tác giả chính: Chakraborty, A, Ko, C, Henning, C, Lucko, A, Harris, JM, Chen, F, Zhuang, X, Wettengel, JM, Roessler, S, Protzer, U, McKeating, JA
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Wiley 2020