Synchronised infection identifies early rate‐limiting steps in the hepatitis B virus life cycle

Hepatitis B virus (HBV) is an enveloped DNA virus that contains a partially double‐stranded relaxed circular (rc) DNA. Upon infection, rcDNA is delivered to the nucleus where it is repaired to covalently closed circular (ccc) DNA that serves as the transcription template for all viral RNAs. Our unde...

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Main Authors: Chakraborty, A, Ko, C, Henning, C, Lucko, A, Harris, JM, Chen, F, Zhuang, X, Wettengel, JM, Roessler, S, Protzer, U, McKeating, JA
格式: Journal article
语言:English
出版: Wiley 2020