Structural evolution of p53, p63, and p73: implication for heterotetramer formation.

Structural evolution of p53, p63, and p73: implication for heterotetramer formation.

Oligomerization of members of the p53 family of transcription factors (p53, p63, and p73) is essential for their distinct functions in cell-cycle control and development. To elucidate the molecular basis for tetramer formation of the various family members, we solved the crystal structure of the hum...

Полное описание

Библиографические подробности
Главные авторы:	Joerger, A, Rajagopalan, S, Natan, E, Veprintsev, D, Robinson, C, Fersht, A
Формат:	Journal article
Язык:	English
Опубликовано:	2009

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