Effective preparation of Plasmodium vivax field isolates for high-throughput whole genome sequencing

Whole genome sequencing (WGS) of Plasmodium vivax is problematic due to the reliance on clinical isolates which are generally low in parasitaemia and sample volume. Furthermore, clinical isolates contain a significant contaminating background of host DNA which confounds efforts to map short read seq...

Cijeli opis

Bibliografski detalji
Glavni autori: Auburn, S, Marfurt, J, Maslen, G, Campino, S, Ruano Rubio, V, Manske, M, Machunter, B, Kenangalem, E, Noviyanti, R, Trianty, L, Sebayang, B, Wirjanata, G, Sriprawat, K, Alcock, D, Macinnis, B, Miotto, O, Clark, T, Russell, B, Anstey, N, Nosten, F, Kwiatkowski, D, Price, R
Format: Journal article
Jezik:English
Izdano: Public Library of Science 2013