Effective preparation of Plasmodium vivax field isolates for high-throughput whole genome sequencing

Whole genome sequencing (WGS) of Plasmodium vivax is problematic due to the reliance on clinical isolates which are generally low in parasitaemia and sample volume. Furthermore, clinical isolates contain a significant contaminating background of host DNA which confounds efforts to map short read seq...

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מידע ביבליוגרפי
Main Authors: Auburn, S, Marfurt, J, Maslen, G, Campino, S, Ruano Rubio, V, Manske, M, Machunter, B, Kenangalem, E, Noviyanti, R, Trianty, L, Sebayang, B, Wirjanata, G, Sriprawat, K, Alcock, D, Macinnis, B, Miotto, O, Clark, T, Russell, B, Anstey, N, Nosten, F, Kwiatkowski, D, Price, R
פורמט: Journal article
שפה:English
יצא לאור: Public Library of Science 2013