The role of BET attenuation in melanoma

The role of BET attenuation in melanoma

Bromodomain and extra-terminal (BETs) proteins function as epigenetic readers by docking onto acetylated lysine residues (Kac) on histone tails via tandem bromodomains (BRDs), and recruiting protein binding partners via an extra-terminal recruitment domain (ET). Targeting BET BRDs is efficacious in...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Henderson, EK
Awduron Eraill:	Filippakopoulos, P
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2020
Pynciau:	Melanoma p53 Cancer Skin cancer Prostate cancer BET proteins

Eitemau Tebyg

Impaired T cell proliferation by ex vivo BET-inhibition impedes adoptive immunotherapy in a murine melanoma model
gan: Jonathan Chee, et al.
Cyhoeddwyd: (2020-02-01)

Bydgoszcz universities students' awareness about melanoma
gan: Katarzyna Mirończuk, et al.
Cyhoeddwyd: (2017-08-01)

Bydgoszcz universities students' awareness about melanoma
gan: Katarzyna Mirończuk, et al.
Cyhoeddwyd: (2017-08-01)

Malignant melanoma and spina bifida
gan: Sarah O'Mahony, et al.
Cyhoeddwyd: (2024-09-01)

Co‐targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor‐resistant melanoma
gan: Ileabett M Echevarría‐Vargas, et al.
Cyhoeddwyd: (2018-04-01)

Targeting BET Proteins Decreases Hyaluronidase-1 in Pancreatic Cancer
gan: Krishan Kumar, et al.
Cyhoeddwyd: (2023-05-01)

The MDM2 inhibitor CGM097 combined with the BET inhibitor OTX015 induces cell death and inhibits tumor growth in models of neuroblastoma
gan: Tyler Maser, et al.
Cyhoeddwyd: (2020-11-01)

The role of artificial intelligence in cancer diagnostics - a review
gan: Paweł Stanicki, et al.
Cyhoeddwyd: (2021-09-01)

A Comprehensive Review of BET Protein Biochemistry, Physiology, and Pathological Roles
gan: Hafiz Akbar Ali, et al.
Cyhoeddwyd: (2022-03-01)

Correlation of p53 immunoexpression with DNA ploidy and apoptotic index in subsets of prostate cancer: A marker reiterated in progression and recurrence of prostate cancer
gan: Anju Bansal, et al.
Cyhoeddwyd: (2015-01-01)

The role of SNPs in the management of cancer in the broader population
gan: Kitchen-Smith, I
Cyhoeddwyd: (2020)

Determinants of problem sports betting among college students: moderating roles of betting frequency and impulsive betting tendency
gan: Yawen Shen
Cyhoeddwyd: (2023-10-01)

Hedging on Betting Markets
gan: Gustav Axén, et al.
Cyhoeddwyd: (2020-08-01)

Home bias in sport betting: Evidence from Czech betting market
gan: Rostislav Staněk
Cyhoeddwyd: (2017-03-01)

High expression of Talin-1 is associated with tumor progression and recurrence in melanoma skin cancer patients
gan: Yasaman Rezaie, et al.
Cyhoeddwyd: (2023-04-01)

Early Detection of Melanoma Skin Cancer
gan: Faruk Alendar, et al.
Cyhoeddwyd: (2009-02-01)

Exploring Melanoma Dynamics: Insights from a 3D Cell Culture Model with Vemurafenib Treatment
gan: Tholstrup Rikke, et al.
Cyhoeddwyd: (2024-01-01)

The BET degrader ZBC260 suppresses stemness and tumorigenesis and promotes differentiation in triple-negative breast cancer by disrupting inflammatory signaling
gan: Deeksha Sharma, et al.
Cyhoeddwyd: (2023-11-01)

The emerging role of BET inhibitors in breast cancer
gan: Angeliki Andrikopoulou, et al.
Cyhoeddwyd: (2020-10-01)

Not Your Mother’s Melanoma: Causes and Effects of Early Melanoma Diagnosis
gan: Kaviyon Sadrolashrafi, et al.
Cyhoeddwyd: (2022-11-01)

Cisplatin and Paclitaxel Modulated the Cell Survival Potential of Prostate Cancer Cells
gan: Sina Kashani, et al.
Cyhoeddwyd: (2020-01-01)

Home bias in sport betting: Evidence from Czech betting market
gan: Rostislav Staněk
Cyhoeddwyd: (2017-03-01)

Cytotoxic Evaluation of Some Fused Pyridazino- and Pyrrolo-quinazolinones Derivatives on Melanoma and Prostate Cell Lines
gan: Golnaz Vaseghi, et al.
Cyhoeddwyd: (2017-01-01)

Higher Numbers of T-Bet+ Tumor-Infiltrating Lymphocytes Associate with Better Survival in Human Epithelial Ovarian Cancer
gan: Yun Xu, et al.
Cyhoeddwyd: (2017-01-01)

Diagnostic Accuracy and Safety of Teledermoscopy for Cutaneous Melanoma Triage in Northern Sweden
gan: Virginia Zazo, et al.
Cyhoeddwyd: (2024-02-01)

Epidemiological Manifestations and Risk Assessment of Melanoma and other Skin Cancers in Altaiskiy Krai
gan: A. I. Blokh, et al.
Cyhoeddwyd: (2018-10-01)

Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition
gan: Wendy Mao, et al.
Cyhoeddwyd: (2019-10-01)

Metformin: Focus on Melanoma
gan: Emilie Jaune, et al.
Cyhoeddwyd: (2018-08-01)

Effects of expertise on football betting
gan: Khazaal Yasser, et al.
Cyhoeddwyd: (2012-05-01)

Prostate Cancer and Li-Fraumeni Syndrome: Implications for Screening and Therapy
gan: Colleen K. Spees, et al.
Cyhoeddwyd: (2015-03-01)

PLASTIC RESTORATION OF A FACIAL DEFECT AFTER SURGICAL REMOVAL OF A LARGE MALIGNANT MELANOMA
gan: Rosen B. TSOLOV
Cyhoeddwyd: (2022-09-01)

Noninvasive Real-Time Automated Skin Lesion Analysis System for Melanoma Early Detection and Prevention
gan: Omar Abuzaghleh, et al.
Cyhoeddwyd: (2015-01-01)

Epidemiological trends in skin cancer
gan: Zoe Apalla, et al.
Cyhoeddwyd: (2017-05-01)

Desmoplastic melanoma presenting as an alopecic patch in a young patient
gan: Lauren C. LaMonica, MPH, et al.
Cyhoeddwyd: (2023-08-01)

Acral Lentiginous Melanoma of the Thumb: Dermoscopy and Treatment
gan: Antonella Tammaro, et al.
Cyhoeddwyd: (2023-09-01)

Dermoscopic Features of Amelanotic and Hypomelanotic Melanomas: A Review of 49 Cases
gan: Sarah Dawood, et al.
Cyhoeddwyd: (2022-05-01)

Editorial: New strategies for the treatment of advanced melanoma and non-melanoma skin cancer
gan: Alessia Villani, et al.
Cyhoeddwyd: (2024-01-01)

The association between TP53 Arg72pro polymorphism and non-melanoma skin cancer risk: A meta-analysis including 7,107 subjects
gan: Xueling Yang, et al.
Cyhoeddwyd: (2013-01-01)

Assessing the Efficacy of the Spectrum-Aided Vision Enhancer (SAVE) to Detect Acral Lentiginous Melanoma, Melanoma In Situ, Nodular Melanoma, and Superficial Spreading Melanoma
gan: Teng-Li Lin, et al.
Cyhoeddwyd: (2024-08-01)

The Immunotherapeutic Role of Type I and III Interferons in Melanoma and Non-Melanoma Skin Cancers
gan: Sydney A. Weir, et al.
Cyhoeddwyd: (2023-06-01)