Canonical Notch signaling is dispensible for adult steady-state and stress myelo-erythropoiesis

Canonical Notch signaling is dispensible for adult steady-state and stress myelo-erythropoiesis

While an essential role for canonical Notch signaling in generation of hematopoietic stem cells in the embryo and in thymic T cell development is well established, its role in adult bone marrow (BM) myelopoiesis remains unclear. Some studies, analyzing myeloid progenitors in adult mice with inhibite...

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Autors principals: Duarte, S, Woll, P, Buza-Vidas, N, Chin, D, Boukarabila, H, Luís, T, Stenson, L, Bouriez-Jones, T, Ferry, H, Mead, A, Atkinson, D, Jin, S, Clark, S, Wu, B, Repapi, E, Gray, N, Taylor, S, Mutvei, A, Tsoi, Y, Nerlov, C, Lendahl, U, Jacobsen, S
Format: Journal article
Idioma:English
Publicat: American Society of Hematology 2018

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