Video-rate nonlinear microscopy of neuronal membrane dynamics with genetically encoded probes.

Biological membranes decorated with suitable contrast agents give rise to nonlinear optical signals such as two-photon fluorescence and harmonic up-conversion when illuminated with ultra-short, high-intensity pulses of infrared laser light. Microscopic images based on these nonlinear contrasts were...

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Bibliographic Details
Main Authors: Roorda, R, Hohl, T, Toledo-Crow, R, Miesenböck, G
Format: Journal article
Language:English
Published: 2004