Targeting intracellular mediators of pattern-recognition receptor signalling to adjuvant vaccination

PRR (pattern-recognition receptor) signalling is involved early in the immune response and therefore would be attractive to target during vaccination. The use of PRR ligands has shown some success; however, toxicity and non-specificity are issues with this strategy. The targeting of PRR intracellula...

Full description

Bibliographic Details
Main Authors: Wales, J, Andreakos, E, Feldmann, M, Foxwell, B
Format: Journal article
Language:English
Published: 2007