A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria

A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria

<br xmlns:etd="http://www.ouls.ox.ac.uk/ora/modsextensions">Due to the widespread prevalence of resistant parasites, chloroquine (CQ) was removed from front-line antimalarial chemotherapy in the 1990s despite its initial promise of disease eradication. Since then, resistance-conferri...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Ch'Ng, J, Mok, S, Bozdech, Z, Lear, M, Boudhar, A, Russell, B, Nosten, F, Tan, K
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	Springer Nature 2013

Παρόμοια τεκμήρια

A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria
ανά: Ch'ng, Jun-Hong, κ.ά.
Έκδοση: (2013)

Overcoming chloroquine resistance in malaria: Design, synthesis and structure-activity relationships of novel chemoreversal agents.
ανά: Boudhar, A, κ.ά.
Έκδοση: (2016)

Validation of a chloroquine-induced cell death mechanism for clinical use against malaria.
ανά: Ch'ng, J, κ.ά.
Έκδοση: (2014)

Comparison of artemether and chloroquine for severe malaria in Gambian children.
ανά: White, N, κ.ά.
Έκδοση: (1992)

Comparison of the umulative efficacy and safety of chloroquine, artesunate, and chloroquine-primaquine in Plasmodium vivax malaria
ανά: Chu, C, κ.ά.
Έκδοση: (2018)

Comparison of the cumulative efficacy and safety of chloroquine, artesunate, and chloroquine-primaquine in plasmodium vivax malaria
ανά: Chu, C, κ.ά.
Έκδοση: (2018)

Chloroquine pharmacokinetics in pregnant and nonpregnant women with vivax malaria.
ανά: Lee, S, κ.ά.
Έκδοση: (2008)

The treatment of chloroquine-resistant malaria.
ανά: van Vugt, M, κ.ά.
Έκδοση: (1999)

The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites.
ανά: Bozdech, Z, κ.ά.
Έκδοση: (2008)

Plasma chloroquine concentrations in young and older malaria patients treated with chloroquine.
ανά: Maitland, K, κ.ά.
Έκδοση: (1997)

Failure of chloroquine-erythromycin and chloroquine-tetracycline combinations in treatment of chloroquine-resistant falciparum malaria in eastern Thailand.
ανά: Phillips, R, κ.ά.
Έκδοση: (1984)

Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand.
ανά: Rijken, M, κ.ά.
Έκδοση: (2011)

Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay
ανά: Loh, C, κ.ά.
Έκδοση: (2014)

Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand
ανά: McGready Rose, κ.ά.
Έκδοση: (2011-05-01)

Chloroquine for the treatment of uncomplicated malaria in Guyana.
ανά: Baird, J, κ.ά.
Έκδοση: (2002)

Parenteral chloroquine for treating falciparum malaria.
ανά: White, N, κ.ά.
Έκδοση: (1987)

Battling the malaria iceberg with chloroquine in India
ανά: Sharma Vinod P
Έκδοση: (2007-08-01)

Diagnosis of resistance to chloroquine by Plasmodium vivax: timing of recurrence and whole blood chloroquine levels.
ανά: Baird, J, κ.ά.
Έκδοση: (1997)

Open comparison of intramuscular chloroquine and quinine in children with severe chloroquine-sensitive falciparum malaria.
ανά: White, N, κ.ά.
Έκδοση: (1989)

Dihydroartemisinin-piperaquine versus chloroquine in the treatment of Plasmodium vivax malaria in Thailand: a randomized controlled trial.
ανά: Phyo, A, κ.ά.
Έκδοση: (2011)

Methylene blue inhibits the asexual development of vivax malaria parasites from a region of increasing chloroquine resistance.
ανά: Suwanarusk, R, κ.ά.
Έκδοση: (2015)

Resistance to chloroquine unhinges vivax malaria therapeutics.
ανά: Baird, J
Έκδοση: (2011)

HPD-induced reversal of chloroquine resistance of malaria
ανά: F. Sogandares-Bernal, κ.ά.
Έκδοση: (1986-01-01)

Combating multidrug-resistant Plasmodium falciparum malaria.
ανά: Thu, A, κ.ά.
Έκδοση: (2017)

Antiplasmodial and chloroquine chemosensitizing and resistance reversal effects of coumarin derivatives against Plasmodium falciparum 3D7 and K1
ανά: O. Ibraheem, Zaid, κ.ά.
Έκδοση: (2016)

Chloroquine-primaquine versus chloroquine alone to treat Vivax malaria in Afghanistan: An open randomized superiority trial.
ανά: Awab, G, κ.ά.
Έκδοση: (2017)

Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay.
ανά: Cheryl C Y Loh, κ.ά.
Έκδοση: (2014-01-01)

Chloroquine has shown high therapeutic efficacy against uncomplicated Plasmodium vivax malaria in southern Ethiopia: seven decades after its introduction
ανά: Mare, AK, κ.ά.
Έκδοση: (2024)

Chloroquine has shown high therapeutic efficacy against uncomplicated Plasmodium vivax malaria in southern Ethiopia: seven decades after its introduction
ανά: Anteneh Kassahun Mare, κ.ά.
Έκδοση: (2024-06-01)

Chloroquine-resistant Plasmodium malariae in south Sumatra, Indonesia.
ανά: Maguire, J, κ.ά.
Έκδοση: (2002)

Does chloroquine cause hypoglycaemia in the absence of clinical malaria?
ανά: Ogbuokiri, J, κ.ά.
Έκδοση: (1987)

Progression of malaria induced pathogenicity during chloroquine therapy
ανά: O. I., Zaid, κ.ά.
Έκδοση: (2020)

Genetics of chloroquine-resistant malaria: a haplotypic view
ανά: Gauri Awasthi, κ.ά.
Έκδοση: (2013-12-01)

The effectiveness of chloroquine compared to Fansidar in treating falciparum malaria
ανά: Emil Azlin, κ.ά.
Έκδοση: (2016-10-01)

The natural function of the malaria parasite’s chloroquine resistance transporter
ανά: Sarah H. Shafik, κ.ά.
Έκδοση: (2020-08-01)

Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancy
ανά: Greenwood Brian, κ.ά.
Έκδοση: (2008-12-01)

Efficacy of Chloroquine for the Treatment of Vivax malaria in Northwest Ethiopia.
ανά: Habtamu Bedimo Beyene, κ.ά.
Έκδοση: (2016-01-01)

Plasma and whole blood mefloquine concentrations during treatment of chloroquine-resistant falciparum malaria with the combination mefloquine-sulphadoxine-pyrimethamine.
ανά: Karbwang, J, κ.ά.
Έκδοση: (1987)

Chloroquine sulphate and chloroquine phosphate (chloroquine diphosphate)
ανά: 982 SIRIM

Plasmodium vivax trophozoites insensitive to chloroquine.
ανά: Sharrock, W, κ.ά.
Έκδοση: (2008)