Molecular mechanisms of dysfunction of muscle fibres associated with Glu139 deletion in TPM2 gene

Geahča maid

• The reason for a high Ca2+-sensitivity associated with Arg91Gly substitution in TPM2 gene is the abnormal behavior and high flexibility of tropomyosin during the ATPase cycle
  Dahkki: Borovikov, Y, et al.
  Almmustuhtton: (2017)
• The effect of the Asp175Asn and Glu180Gly TPM1 mutations on actin-myosin interaction during the ATPase cycle.
  Dahkki: Rysev, N, et al.
  Almmustuhtton: (2012)
• The effect of the dilated cardiomyopathy-causing Glu40Lys TPM1 mutation on actin-myosin interactions during the ATPase cycle.
  Dahkki: Borovikov, Y, et al.
  Almmustuhtton: (2011)
• The effect of the dilated cardiomyopathy-causing Glu40Lys TPM1 mutation on actin-myosin interactions during the ATPase cycle
  Dahkki: Borovikov, Y, et al.
  Almmustuhtton: (2011)
• Hypertrophic cardiomyopathy-causing Asp175asn and Glu180gly Tpm1 mutations shift tropomyosin strands further towards the open position during the ATPase cycle
  Dahkki: Borovikov, Y, et al.
  Almmustuhtton: (2011)