Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe

HIV-1 set-point viral load-the approximately stable value of viraemia in the first years of chronic infection-is a strong predictor of clinical outcome and is highly variable across infected individuals. To better understand HIV-1 pathogenesis and the evolution of the viral population, we must quant...

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Bibliographic Details
Main Authors: Blanquart, F, Wymant, C, Cornelissen, M, Gall, A, Bakker, M, Bezemer, D, Hall, M, Hillebregt, M, Ong, S, Albert, J, Bannert, N, Fellay, J, Fransen, K, Gourlay, A, Grabowski, M, Gunsenheimer-Bartmeyer, B, Günthard, H, Kivelä, P, Kouyos, R, Laeyendecker, O, Liitsola, K, Meyer, L, Porter, K, Ristola, M, van Sighem, A, Vanham, G, Berkhout, B, Kellam, P, Reiss, P, Fraser, C, BEEHIVE collaboration
Format: Journal article
Language:English
Published: Public Library of Science 2017