Three-dimensional super-resolution in eukaryotic cells using the double-helix point spread function

Single-molecule localization microscopy, typically based on total internal reflection illumination, has taken our understanding of protein organization and dynamics in cells beyond the diffraction limit. However, biological systems exist in a complicated three-dimensional environment, which has requ...

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Bibliographic Details
Main Authors: Carr, AR, Ponjavic, A, Basu, S, McColl, J, Santos, AM, Davis, S, Laue, ED, Klenerman, D, Lee, SF
Format: Journal article
Language:English
Published: Elsevier 2017