A comparison of the pharmacokinetic and pharmacodynamic properties of quinine and quinidine in healthy Thai males.

1. Eight healthy Thai males, aged 19-27 years, received quinine or quinidine dihydrochloride 10 mg kg-1 body weight by intravenous infusion over 1 h. At least 1 week later, the alternative alkaloid was administered. 2. The terminal elimination half-time of quinidine was shorter than that of quinine...

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Detalhes bibliográficos
Main Authors: Karbwang, J, Davis, T, Looareesuwan, S, Molunto, P, Bunnag, D, White, N
Formato: Journal article
Idioma:English
Publicado em: 1993