GDF15 mediates the effects of metformin on body weight and energy balance

Metformin, the world’s most prescribed anti-diabetic drug, is also effective in preventing type 2 diabetes in people at high risk1,2. More than 60% of this effect is attributable to the ability of metformin to lower body weight in a sustained manner3. The molecular mechanisms by which metformin lowe...

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Bibliographic Details
Main Authors: Coll, A, Chen, M, Taskar, P, Preiss, D, et al.
Format: Journal article
Language:English
Published: Nature Research 2019