B-cell tolerance.
Autoreactive B cells are actively tolerized to more abundant self-antigens by a series of checkpoints involving receptor editing, deletion, anergy and competition for growth factors. In contrast, B cells reactive against rare, sequestered or tissue specific self-antigens remain functionally naïve. D...
প্রধান লেখক: | , , , , , , |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
2006
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