L-Carnitine stimulates in vivo carbohydrate metabolism in the Type 1 diabetic heart as demonstrated by hyperpolarized MRI

The diabetic heart is energetically and metabolically abnormal, with increased fatty acid oxidation and decreased glucose oxidation. One factor contributing to the metabolic dysfunction in diabetes may be abnormal handling of acetyl and acyl groups by the mitochondria. L-carnitine is responsible for...

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Bibliographic Details
Main Authors: Savic, D, Ball, V, Curtis, MK, Sousa Fialho, MDL, Timm, KN, Hauton, D, West, J, Griffin, J, Heather, LC, Tyler, DJ
Format: Journal article
Language:English
Published: MDPI 2021