Interleukin 10-mediated immunosuppression by a variant CD4 T cell epitope of Plasmodium falciparum.

The immunodominant CD4 T cell epitope region, Th2R, of the circumsporozoite protein of Plasmodium falciparum is highly polymorphic. Such variation might be utilized by the parasite to escape from or interfere with CD4 T cell effector functions. Here, we show that costimulation with naturally occurri...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Plebanski, M, Flanagan, K, Lee, E, Reece, W, Hart, K, Gelder, C, Gillespie, G, Pinder, M, Hill, A
Format: Journal article
Język:English
Wydane: 1999