DNA Instability in premature aging

DNA damage accumulates with increased chronological age and may contribute to both cell senescence and cancer. However, the importance and role(s) of DNA damage in promoting ageing is difficult to analyze experimentally at the molecular level since ageing results from a complex interplay of genetic...

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Bibliographic Details
Main Authors: Cox, L, Boubriak, I
Format: Book section
Published: Nova Science Publishers, Inc. 2012