GATA3 mutations found in breast cancers may be associated with aberrant nuclear localization, reduced transactivation and cell invasiveness.

Somatic and germline mutations in the dual zinc-finger transcription factor GATA3 are associated with breast cancers expressing the estrogen receptor (ER) and the autosomal dominant hypoparathyroidism-deafness-renal dysplasia syndrome, respectively. To elucidate the role of GATA3 in breast tumorigen...

詳細記述

書誌詳細
主要な著者: Gaynor, K, Grigorieva, I, Allen, MD, Esapa, C, Head, R, Gopinath, P, Christie, P, Nesbit, M, Jones, J, Thakker, R
フォーマット: Journal article
言語:English
出版事項: 2013