The mouse Runx1 +23 hematopoietic stem cell enhancer confers hematopoietic specificity to both Runx1 promoters.
The transcription factor Runx1 plays a pivotal role in hematopoietic stem cell (HSC) emergence, and studies into its transcriptional regulation should give insight into the critical steps of HSC specification. Recently, we identified the Runx1 +23 enhancer that targets reporter gene expression to th...
المؤلفون الرئيسيون: | Bee, T, Ashley, E, Bickley, SR, Jarratt, A, Li, P, Sloane-Stanley, J, Göttgens, B, de Bruijn, M |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2009
|
مواد مشابهة
-
THE RUNX1+23 ENHANCER IS ACTIVE IN CELLS WITH BOTH ENDOTHELIAL AND HEMATOPOIETIC CHARACTERISTICS DURING MOUSE DEVELOPMENTAL HEMATOPOIESIS
حسب: Swiers, G, وآخرون
منشور في: (2009) -
Alternative Runx1 promoter usage in mouse developmental hematopoiesis.
حسب: Bee, T, وآخرون
منشور في: (2009) -
Hematopoietic stem cell emergence in the conceptus and the role of Runx1.
حسب: Swiers, G, وآخرون
منشور في: (2010) -
An intronic Runx1 enhancer directs transcription to the emerging hematopoietic system of the mouse embryo
حسب: Nottingham, W, وآخرون
منشور في: (2007) -
Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer.
حسب: Nottingham, W, وآخرون
منشور في: (2007)