Effect of protein kinase C modulators on the leucocyte Na+/H+ antiport in type 1 (insulin-dependent) diabetic subjects with albuminuria.

It is uncertain why only one third of Type 1 (insulin-dependent) diabetic patients develop nephropathy. One suggestion is the inheritance of a predisposition to essential hypertension. We have previously found elevated Na+/H+ antiport activity and a raised intracellular pH in leucocytes from hyperte...

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Bibliographic Details
Main Authors: Ng, L, Simmons, D, Frighi, V, Garrido, M, Bomford, J
Format: Journal article
Language:English
Published: Springer-Verlag 1990