Synergistic DNA-MVA prime-boost vaccination regimes for malaria and tuberculosis.

T-cell-mediated responses against the liver-stage of Plasmodium falciparum are critical for protection in the human irradiated sporozoite model and several animal models. Heterologous prime-boost approaches, employing plasmid DNA and viral vector delivery of malarial DNA sequences, have proved parti...

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Bibliographic Details
Main Authors: Gilbert, S, Moorthy, V, Andrews, L, Pathan, A, McConkey, S, Vuola, J, Keating, S, Berthoud, T, Webster, D, Mcshane, H, Hill, A
Format: Journal article
Language:English
Published: 2006