Synergistic DNA-MVA prime-boost vaccination regimes for malaria and tuberculosis.
T-cell-mediated responses against the liver-stage of Plasmodium falciparum are critical for protection in the human irradiated sporozoite model and several animal models. Heterologous prime-boost approaches, employing plasmid DNA and viral vector delivery of malarial DNA sequences, have proved parti...
Main Authors: | , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2006
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