Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

The 10q26 locus in the second intron of FGFR2 is the locus most strongly associated with estrogen-receptor-positive breast cancer in genome-wide association studies. We conducted fine-scale mapping in case-control studies genotyped with a custom chip (iCOGS), comprising 41 studies (n = 89,050) of Eu...

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Bibliographic Details
Main Authors: Meyer, K, O'Reilly, M, Michailidou, K, Carlebur, S, Edwards, S, French, J, Prathalingham, R, Dennis, J, Bolla, M, Wang, Q, de Santiago, I, Hopper, J, Tsimiklis, H, Apicella, C, Southey, M, Schmidt, M, Broeks, A, Van 't Veer, L, Hogervorst, F, Muir, K, Lophatananon, A, Stewart-Brown, S, Siriwanarangsan, P, Fasching, P, Lux, M
Format: Journal article
Language:English
Published: 2013