A TFEB nuclear export signal integrates amino acid supply and glucose availability
How cells coordinate the response to fluctuating carbon and nitrogen availability required to maintain effective homeostasis is a key issue. Amino acid limitation that inactivates mTORC1 promotes de-phosphorylation and nuclear translocation of Transcription Factor EB (TFEB), a key transcriptional re...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Springer Nature
2018
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