APC mutations in FAP-associated desmoid tumours are non-random but not 'just right'.
Analysis of APC mutations in colonic and duodenal tumours from familial adenomatous polyposis (FAP) patients has shown that the site of the first hit, the germline mutation, can predict the type and position of the somatic mutation or 'second hit'. The two APC mutations are selected on the...
Հիմնական հեղինակներ: | Latchford, A, Volikos, E, Johnson, V, Rogers, P, Suraweera, N, Tomlinson, I, Phillips, R, Silver, A |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2007
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Նմանատիպ նյութեր
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Evidence for genetic predisposition to desmoid tumours in familial adenomatous polyposis independent of the germline APC mutation.
: Sturt, N, և այլն
Հրապարակվել է: (2004) -
A Patient With Desmoid Tumors and Familial FAP Having Frame Shift Mutation of the APC Gene
: Sanambar Sadighi, և այլն
Հրապարակվել է: (2017-02-01) -
Location in the large bowel influences the APC mutations observed in FAP adenomas.
: Will, O, և այլն
Հրապարակվել է: (2010) -
A novel exon duplication event leading to a truncating germ-line mutation of the APC gene in a familial adenomatous polyposis family.
: McCart, A, և այլն
Հրապարակվել է: (2006) -
Pregnancy does not influence colonic polyp multiplicity but may modulate upper gastrointestinal disease in patients with FAP.
: Suraweera, N, և այլն
Հրապարակվել է: (2007)