Calcium handling precedes cardiac differentiation to initiate the first heart beat

Calcium handling precedes cardiac differentiation to initiate the first heart beat

The mammalian heartbeat is thought to begin just prior to the linear heart tube stage of development. How the initial contractions are established and the downstream consequences of the earliest contractile function on cardiac differentiation and morphogenesis have not been described. Using high-res...

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Autors principals:	Tyser, R, Miranda, A, Chen, C, Davidson, S, Srinivas, S, Riley, P
Format:	Journal article
Publicat:	eLife Sciences Publications 2016

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