Detection of plasmid DNA vectors following gene transfer to the murine airways.

Non-viral gene therapy is being considered as a treatment for cystic fibrosis. In clinical studies and in studies using the mouse airways as a model, current formulations result in only transient transgene expression. A number of reasons for this have been proposed including the loss of plasmid DNA...

Descripción completa

Detalles Bibliográficos
Autores principales: Pringle, I, Raman, S, Sharp, W, Cheng, S, Hyde, S, Gill, DR
Formato: Journal article
Lenguaje:English
Publicado: 2005