Detection of plasmid DNA vectors following gene transfer to the murine airways.

Non-viral gene therapy is being considered as a treatment for cystic fibrosis. In clinical studies and in studies using the mouse airways as a model, current formulations result in only transient transgene expression. A number of reasons for this have been proposed including the loss of plasmid DNA...

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Bibliographic Details
Main Authors: Pringle, I, Raman, S, Sharp, W, Cheng, S, Hyde, S, Gill, DR
Format: Journal article
Language:English
Published: 2005