Terminate and make a loop: regulation of transcriptional directionality

Bidirectional promoters are a common feature of many eukaryotic organisms from yeast to humans. RNA Polymerase II that is recruited to this type of promoter can start transcribing in either direction using alternative DNA strands as the template. Such promiscuous transcription can lead to the synthe...

Полное описание

Библиографические подробности
Главные авторы: Tan-Wong, S, Grzechnik, P, Proudfoot, N
Формат: Journal article
Опубликовано: Elsevier 2014