p120 catenin reduction and cytoplasmic relocalization leads to dysregulation of E-cadherin in solid pseudopapillary tumors of the pancreas.
Solid pseudopapillary tumors (SPTs) of the pancreas have characteristic morphologic features and show consistent beta-catenin abnormalities and loss of E-cadherin protein. The loss of cell-to-cell adhesion is thought to contribute to frequent cystic degeneration and pseudopapillae formation. p120 re...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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