The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt
The Notch pathway plays a vital role in determining whether cells in the intestinal epithelium adopt a secretory or an absorptive phenotype. Cell fate specification is coordinated via Notch's interaction with the canonical Wnt pathway. Here, we propose a new mathematical model of the Notch and...
| Main Authors: | , , , , , , , |
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| Format: | Journal article |
| Udgivet: |
Public Library of Science
2017
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