A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein

Immunization with attenuated Plasmodium falciparum sporozoites (PfSPZs) has been shown to be protective against malaria, but the features of the antibody response induced by this treatment remain unclear. To investigate this response in detail, we isolated IgM and IgG monoclonal antibodies from Tanz...

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Príomhchruthaitheoirí: Tan, J, Sack, B, Oyen, D, Zenklusen, I, Piccoli, L, Barbieri, S, Foglierini, M, Fregni, C, Marcandalli, J, Jongo, S, Abdulla, S, Perez, L, Corradin, G, Varani, L, Sallusto, F, Sim, B, Hoffman, S, Kappe, S, Daubenberger, C, Wilson, I, Lanzavecchia, A
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: Springer Nature 2018

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