A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein

A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein

Immunization with attenuated Plasmodium falciparum sporozoites (PfSPZs) has been shown to be protective against malaria, but the features of the antibody response induced by this treatment remain unclear. To investigate this response in detail, we isolated IgM and IgG monoclonal antibodies from Tanz...

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Bibliografische gegevens
Hoofdauteurs:	Tan, J, Sack, B, Oyen, D, Zenklusen, I, Piccoli, L, Barbieri, S, Foglierini, M, Fregni, C, Marcandalli, J, Jongo, S, Abdulla, S, Perez, L, Corradin, G, Varani, L, Sallusto, F, Sim, B, Hoffman, S, Kappe, S, Daubenberger, C, Wilson, I, Lanzavecchia, A
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	Springer Nature 2018

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