An aryne-based route to substituted benzoisothiazoles

The combination of arynes, generated using fluoride from the corresponding 2-(trimethylsilyl)aryl triflates, and 3-hydroxy-4-aminothiadiazoles leads to the selective formation of 3-amino-substituted benzo[d]isothiazoles. Variation of the substitution pattern of the aryne precursor, and of the thiadi...

Descripció completa

Dades bibliogràfiques
Autors principals: Chen, Y, Willis, MC
Format: Journal article
Idioma:English
Publicat: American Chemical Society 2015