An aryne-based route to substituted benzoisothiazoles
The combination of arynes, generated using fluoride from the corresponding 2-(trimethylsilyl)aryl triflates, and 3-hydroxy-4-aminothiadiazoles leads to the selective formation of 3-amino-substituted benzo[d]isothiazoles. Variation of the substitution pattern of the aryne precursor, and of the thiadi...
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| Médium: | Journal article |
| Jazyk: | English |
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American Chemical Society
2015
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