An aryne-based route to substituted benzoisothiazoles

The combination of arynes, generated using fluoride from the corresponding 2-(trimethylsilyl)aryl triflates, and 3-hydroxy-4-aminothiadiazoles leads to the selective formation of 3-amino-substituted benzo[d]isothiazoles. Variation of the substitution pattern of the aryne precursor, and of the thiadi...

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Bibliografske podrobnosti
Main Authors: Chen, Y, Willis, MC
Format: Journal article
Jezik:English
Izdano: American Chemical Society 2015

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