Ibudilast inhibits chemokine expression in rheumatoid synovial fibroblasts and exhibits immunomodulatory activity in experimental arthritis

Ibudilast inhibits chemokine expression in rheumatoid synovial fibroblasts and exhibits immunomodulatory activity in experimental arthritis

<br/><strong>Objective: </strong>Ibudilast is a well‐tolerated, orally available type 4 phosphodiesterase (PDE4) inhibitor used to treat asthma and stroke. As PDE4 inhibition suppresses inflammatory mediator production and cell proliferation in leukocytes, ibudilast may be a valuab...

Полное описание

Библиографические подробности
Главные авторы:	Clanchy, F, Williams, R
Формат:	Journal article
Опубликовано:	Wiley 2018

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