Glycolysis downregulation is a hallmark of HIV‐1 latency and sensitizes infected cells to oxidative stress

HIV‐1 infects lymphoid and myeloid cells, which can harbor a latent proviral reservoir responsible for maintaining lifelong infection. Glycolytic metabolism has been identified as a determinant of susceptibility to HIV‐1 infection, but its role in the development and maintenance of HIV‐1 latency has...

Full description

Bibliographic Details
Main Authors: Shytaj, IL, Procopio, FA, Tarek, M, Carlon‐Andres, I, Tang, H, Goldman, AR, Munshi, M, Kumar Pal, V, Forcato, M, Sreeram, S, Leskov, K, Ye, F, Lucic, B, Cruz, N, Ndhlovu, LC, Bicciato, S, Padilla‐Parra, S, Diaz, RS, Singh, A, Lusic, M, Karn, J, Alvarez‐Carbonell, D, Savarino, A
Format: Journal article
Language:English
Published: Springer 2021