Lysosomal Ca(2+) homeostasis: role in pathogenesis of lysosomal storage diseases.
Disrupted cellular Ca(2+) signaling is believed to play a role in a number of human diseases including lysosomal storage diseases (LSD). LSDs are a group of ∼50 diseases caused predominantly by mutations in lysosomal proteins that result in accumulation of macromolecules within the lysosome. We rece...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2011
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