Lysosomal Ca(2+) homeostasis: role in pathogenesis of lysosomal storage diseases.

Disrupted cellular Ca(2+) signaling is believed to play a role in a number of human diseases including lysosomal storage diseases (LSD). LSDs are a group of ∼50 diseases caused predominantly by mutations in lysosomal proteins that result in accumulation of macromolecules within the lysosome. We rece...

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Príomhchruthaitheoirí: Lloyd-Evans, E, Platt, F
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2011