Lysosomal Ca(2+) homeostasis: role in pathogenesis of lysosomal storage diseases.

Disrupted cellular Ca(2+) signaling is believed to play a role in a number of human diseases including lysosomal storage diseases (LSD). LSDs are a group of ∼50 diseases caused predominantly by mutations in lysosomal proteins that result in accumulation of macromolecules within the lysosome. We rece...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Lloyd-Evans, E, Platt, F
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2011