A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus.

BACKGROUND: Osteoporosis is a systemic skeletal disease characterised by reduced bone mineral density and increased susceptibility to fracture; these traits are highly heritable. Both common and rare copy number variants (CNVs) potentially affect the function of genes and may influence disease risk....

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Main Authors: Oei, L, Hsu, Y, Styrkarsdottir, U, Eussen, B, de Klein, A, Peters, M, Halldorsson, B, Liu, C, Alonso, N, Kaptoge, S, Thorleifsson, G, Hallmans, G, Hocking, L, Husted, L, Jameson, K, Kruk, M, Lewis, JR, Patel, MS, Scollen, S, Svensson, O, Trompet, S, van Schoor, N, Zhu, K, Buckley, B, Cooper, C
Format: Journal article
Language:English
Published: 2014