Protection from Plasmodium berghei infection by priming and boosting T cells to a single class I-restricted epitope with recombinant carriers suitable for human use.

The desirability of inducing cytotoxic T cell responses to defined epitopes in humans has led to the development of a variety of recombinant delivery systems. Recombinant protein particles derived from a yeast retrotransposon (Ty) and the modified Ankara vaccinia (MVA) virus can deliver large epitop...

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Bibliographic Details
Main Authors: Plebanski, M, Gilbert, S, Schneider, J, Hannan, C, Layton, G, Blanchard, T, Becker, M, Smith, G, Butcher, G, Sinden, R, Hill, A
Format: Journal article
Language:English
Published: 1998