MEK1/2 blockade by AZD6244 (ARRY-142886) inhibits tumor growth and progression in an orthotopic human lung adenocarcinoma model with enhanced efficacy when combined with cediranib

Մատենագիտական մանրամասներ
Հիմնական հեղինակներ:	Takahashi, O, Komaki, R, Smith, P, Ryan, A, Jurgensmeier, J, Welsh, J, Jacoby, J, Hosho, K, Korshunova, M, Erez, B, Herbst, R, O'Reilly, MS
Ձևաչափ:	Journal article
Հրապարակվել է:	2009

DOC-MEK: A double-blind randomized phase II trial of docetaxel with or without selumetinib (AZD6244; ARRY-142886) in wt BRAF advanced melanoma
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Author Correction: Targeting inhibition of extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) suppresses growth and angiogenesis of gastric cancer
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Combined MEK and VEGFR inhibition in orthotopic human lung cancer models results in enhanced inhibition of tumor angiogenesis, growth, and metastasis.
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Հրապարակվել է: (2012)

Combined MEK and VEGFR inhibition in orthotopic human lung cancer models results in enhanced inhibition of tumor angiogenesis, growth, and metastasis
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Հրապարակվել է: (2012)

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Հրապարակվել է: (2010)

A phase I, open-label, randomized crossover study to assess the effect of dosing of the MEK 1/2 inhibitor Selumetinib (AZD6244; ARRY-142866) in the presence and absence of food in patients with advanced solid tumors
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Հրապարակվել է: (2011)

A phase I, open-label, randomized crossover study to assess the effect of dosing of the MEK 1/2 inhibitor Selumetinib (AZD6244; ARRY-142866) in the presence and absence of food in patients with advanced solid tumors.
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Հրապարակվել է: (2011)

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Հրապարակվել է: (2010-01-01)

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Antitumor and antiangiogenic activity of cediranib in a preclinical model of renal cell carcinoma.
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Resistance to Selumetinib (AZD6244) in Colorectal Cancer Cell Lines is Mediated by p70S6K and RPS6 Activation
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Հրապարակվել է: (2014-10-01)

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Հրապարակվել է: (2012)

Evaluation of novel combined carbogen USPIO (CUSPIO) imaging biomarkers in assessing the antiangiogenic effects of cediranib (AZD2171) in rat C6 gliomas.
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Հրապարակվել է: (2012)

The effect of food on the single dose pharmacokinetics of cediranib
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Հրապարակվել է: (2008)

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‌: Brown, N, և այլն
Հրապարակվել է: (2016)

Multi-Center Randomized Phase II Study Comparing Cediranib plus Gefitinib with Cediranib plus Placebo in Subjects with Recurrent/Progressive Glioblastoma.
‌: Nicholas Brown, և այլն
Հրապարակվել է: (2016-01-01)

Comparisons of the Efficacy of a Jak1/2 Inhibitor (AZD1480) with a VEGF Signaling Inhibitor (Cediranib) and Sham Treatments in Mouse Tumors Using DCE-MRI, DW-MRI, and Histology
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Հրապարակվել է: (2012-01-01)

Computer interfacing with radial line slot arry (RLSA) antenna measurement /
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Հրապարակվել է: (1999)

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Changes in perfusion and permeability in glioblastoma model induced by the anti-angiogenic agents cediranib and thalidomide
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Synergistic Antivascular and Antitumor Efficacy with Combined Cediranib and SC6889 in Intracranial Mouse Glioma.
‌: Merryl R Lobo, և այլն
Հրապարակվել է: (2015-01-01)

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MEK1/2 blockade by AZD6244 (ARRY-142886) inhibits tumor growth and progression in an orthotopic human lung adenocarcinoma model with enhanced efficacy when combined with cediranib

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